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10-hydroxy-2E-decenoic acidCAS NO : 14113-05-4
MolecularFormula : C10H18O3
Appearance : Colorless crystalline solid
Product name: 10-hydroxy-2E-decenoic acid
Chinese alias: Queen Bee acid; 10-hydroxy-2E-decenoic acid; (E)-10-hydroxy-2-decenoic acid; 10-hydroxydecenoic acid;
English name: Royal jelly acid
CAS: 765-01-5; 14113-05-4
Molecular formula: C10H18O3
Molecular weight: 186.25
Standard: Enterprise Standard
Level: Pharmaceutical Grade
Appearance: white powder
10-hydroxy-2E-decenoic acid is an organic acid separated from royal jelly by Chinese medical scientists. It is one of the important components of royal jelly and a special unsaturated organic acid. Many properties of royal jelly, such as smell and pH value, are related to it.
This acid is also called 10-hydroxy-2E-decenoic acid because it is not found in other substances in nature and is found only in royal jelly. 10 - hydroxy - 2TR-decenoic acid content is one of the important indicators of the quality of royal jelly, with the general content ranging from 1.4% to 2.4%, more than about 50% of total fatty acids. The separated pure 10-hydroxy-2E-decenoic acid is white crystal, mostly exists in free form in fresh royal jelly, has relatively stable properties and has good sterilization, bacteriostasis, anticancer and anti-radiation functions.10 - hydroxy - 2TR-decenoic acid is of great significance to protect the active substances in royal jelly and greatly improves the effectiveness of health care and medical effects of royal jelly.
10-hydroxy-2E-decenoic acid, also known as Queen Bee acid, is a unique active ingredient of royal jelly. It’s content has always been the most important index to measure the quality and distinguish the authenticity of royal jelly in the global trade.For a long time, a large number of studies have been reported on the functions of 10-hydroxy-2E-decenoic acid, mainly including bacteriostasis, lowering blood lipid, anti-tumor, immune regulation, anti-radiation and so on.
Low concentration of 10-hydroxy-2E-decenoic acid can strongly inhibit the growth of bacteria, fungi such as Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Streptococcus, Proteus, Mycobacterium tuberculosis, Trichophyton stellate and trichophyton epidermidis, high concentration has the effect of killing bacteria. It has obvious inhibitory effect on vascular permeability, tissue fluid exudation and edema in the earlystage of inflammation. But it is four times less antibacterial than penicillin and five times less antibacterial than chloramphenicol. In addition, 10-hydroxy-2E-decenoic acid can inhibit the formation of stress ulcer and pyloric ligation and anti-inflammation gastric ulcer, promote the healing of acetic acid gastric ulcer, inhibit gastric acid secretion, and enhance the protective effect of gastric mucosa cells.
10-hydroxy-2E-decenoic acid can promote bone marrow cell division and the synthesis of human peripheral blood lymphocyte deoxyribonucleic acid, stimulate lymphocyte mitosis, make cell transformation and proliferation, and enhance the cellular immune function of the body.
10-hydroxy-2E-decenoic acid has obvious effect on inhibiting the growth of tumor cells , can promote the phagocytic function of phagocytes, and has anti-leukemia and ascites cancer activity.
Studies have shown that 10-hydroxy-2E-decenoic acid can protect and restore visceral proteins, ribonucleic acid and DNA, so it can play a preventive role in acute radiation injury.
10-hydroxy-2E-decenoic acid can improve the fat content in the blood, reduce the fat accumulation and precipitation after the meal, prevent the synthesis of lipid substance, so it has the effect of reducing blood fat. Animal experiments have shown that 10-hydroxy-2E-decenoic acid can reduce the contents of triglyceride (TG), total cholesterol (TC) and total lipoprotein in blood of experimental hyperlipidemia rats, while increasing the content of beneficial high density lipoprotein (HDL).